动画美术指导山本二三因胃癌于8月19日去世，享年70岁。他曾参与过《天空之城》《萤火虫之墓》《幽灵公主》《穿越时空的少女》等多部动画的制作。
山本二三生于1953年，在东京设计学院（现东京COOL JAPAN）学习时，就在动画的美术工作室参与背景绘制，毕业后加入日本动画公司，在TV动画《未来少年柯南》中首次担任美术导演（该作为宫崎骏初次担任导演的TV动画）。1985年，因宫崎骏邀请，山本二三加入吉卜力，在高田勋、宫崎骏的多部作品中负责美术指导和背景。他尤其擅长绘制层次丰富的白云，笔下的云在日本动画界有“二三云”之称。
在游戏《世界树的迷宫IV 传承的巨神》《世界树和不可思议的迷宫》中，山本二三负责背景美术。《世界树迷宫》官推发文对山本的去世表示哀悼，并放出了2张由山本绘制的背景图。
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